CIPA is a rare autosomal recessive, multisystem disease, involving the central nervous system (CNS),2 the peripheral nervous system, and the musculoskeletal, endocrine, ophthalmic, oral, and immunological systems. It is one of five inherited diseases known as hereditary sensory and autonomic neuropathies (HSAN) types 1 to 5; CIPA is HSAN type 4 (HSAN4)
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